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Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... injury R ≤ 2 ... #Enzymes #LFTs ... #Cholestatic #Transaminitis
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... Hepatocellular Pattern #LFTs ... #transaminits #
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
(LFTs) Elevation ... injury >2 ... pattern ≤2: ... #FunctionTest #LFTs ... #Elevation #Transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Tests (LFTs) - ... (Drug-induced liver ... Function #Tests #LFTs ... Diagnosis #hepatology #transaminitis
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Skeletal muscle 2- ... #Patterns #Liver ... Injury #hepatology #LFTs ... #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... Injury → liver ... phosphatase) 2) ... hepatology #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Abscess on POCUS
24yo healthy F to ED w/rigors &DCed. 2/2 blood cx + for fusobacterium,
POCUS 24yo healthy ... /rigors &DCed. 2/ ... 2 blood cx + for ... asymptomatic, CBC/chem/LFTs ... Abscess #Hepatic #POCUS
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Algorithm for Transaminitis ... Burak @kwburak #LFTs ... Elevated #Abnormal #Transaminitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... HCV RNA • R 2- ... HCV RNA • R < 2: ... differential #Hepatology #transaminitis ... #LFTs #RValue #
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
The Liver Consult ... different) PMHx: - Focus ... on prior Liver/ ... - Vitals - LFTs ... US - Prior liver