864 results
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
TRALI vs TACO - Transfusion ... plasma volume transfusion ... blood donor • Pathophysiology ... Within 6 hours of transfusion ... • Pathophysiology
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... 24%) • Fewer transfusions ... Benefits #SickleCell #pathophysiology
Classification of COVID-19 Disease States and Potential Therapeutic Targets

Viral Response Phase -> Host Inflammatory Response Phase
Stage
convalescent plasma transfusions ... Classification #Diagnosis #Pathophysiology
Babesiosis - Babesia Life Cycle
1) Tick takes a blood meal (sporozoites introduced into host)
2) Trophozie ←→
human-to-human via blood transfusion ... LifeCycle #diagnosis #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Diuretics, PRBC transfusion ... Lysis Syndrome: • Pathophysiology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... consider platelet transfusion ... Pressure #ICP #Pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
incompatible blood transfusion ... protein C and S Pathophysiology ... hydration • RBC transfusion
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Evidence Summary for Transfusion ... show that PRBC transfusions ... Unnecessary transfusions ... Transfusions should ... Transfusions are
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
destruction after transfusion ... Classification #Pathophysiology
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Framework NCPE Pathophysiology ... pulmonary edema) • Transfusion-related