10 results
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Platelet Count ... Non-infectious (malignancy, rheumatologic ... , trauma) • Post-splenectomy ... #causes #Platelets ... #hematology
Thromboelastography (TEG) based therapy and Management

If r time prolonged -> FFP
If MA low -> plts/cryoprecipitate (if
cryoprecipitate If platelets ... < 50 - > platelet ... TEG #Management #Diagnosis ... #Hematology #Thromboelastogram
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
Thromboelastogram ... representing thrombin-platelet ... - Treatment: Platelets ... Thromboelastography #diagnosis ... #coagulation #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... → Refer to hematology ... infarction, Severe trauma ... Thrombocytosis #Platelets ... #Algorithm #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
RBC's secondary to platelet ... Thrombocytopenia • Platelet ... NON-PALPABLE PURPURA: Platelet ... Solar purpura - Trauma ... #hematology #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Thrombocytopenia - Abnormal platelet ... integrity: - Trauma ... #Differential #Diagnosis ... Algorithm #Causes #dermatology
THROMBOELASTOGRAPHY (TEG)
General Principle
• A small cuvette is rotated to simulate sluggish venous flow and stimulate clot
coagulation cascade and platelet ... nickmmark #TEG #Thromboelastogram ... Thromboelastography #Diagnosis ... #CriticalCare #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Recent history of trauma ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... #Coagulation #diagnosis ... treatment #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
donor (apheresis) platelets ... transfusion, due to anti-platelet ... common following platelet ... contamination: Platelets ... #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... transfusion, due to anti-platelet ... common following platelet ... contamination: Platelets ... #management #hematology