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hematology differential intravascular anemia arterial bruising cryofibrinogenemia dic disseminated essential et extravascular hemolysis hemolytic inr nonpalpable palpable pathophysiology petechiae petechial
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Algorithm Thrombocytopenia ... #Algorithm #Causes ... #Hematology
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology #coagulation ... #disorders
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... , coagulation disorders ... disorders CAUSES ... Solar purpura - Trauma ... #hematology #rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
• Rheumatic disorders ... Post-op surgery • Trauma ... following EtOH induced thrombocytopenia ... #Algorithm #Causes ... #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Recent history of trauma ... Treat primary cause ... #diagnosis #causes ... #treatment #management ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Surgery • Trauma ... Intravenous Drug Use • Pregnancy ... intravascular coagulation ... and other causes ... pathophysiology #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
• Mechanical Trauma ... intravascular coagulation ... microangiopathy: Thrombotic thrombocytopenic ... lymphoproliferative disorders ... #hematology #anemia
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
hemostasis: - Thrombocytopenia ... integrity: - Trauma ... - Cholesterol embolism ... #Algorithm #Causes ... #dermatology #physicalexam
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Paradoxical spontaneous bleeding ... thrombophlebitis, pulmonary ... cryoglobulins • Negative causes ... #rheumatology # ... hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
first trimester pregnancy ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology
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