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hematology differential anemia arterial atlas bruising coagulation cryofibrinogenemia dic disseminated essential et extravascular hemolysis hemolytic key morphology nonpalpable palpable pathophysiology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Algorithm Thrombocytopenia ... • Disseminated Intravascular ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... • Mechanical Trauma ... microangiopathy: Thrombotic thrombocytopenic ... lymphoproliferative disorders ... #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
• Rheumatic disorders ... Post-op surgery • Trauma ... following EtOH induced thrombocytopenia ... #Algorithm #Causes ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... : - Thrombocytopenia ... Solar purpura - Trauma ... #Differential #Diagnosis ... #hematology #rheumatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Surgery • Trauma ... Intravenous Drug Use • Pregnancy ... - Disseminated intravascular ... coagulation and other causes ... pathophysiology #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Recent history of trauma ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Liver diseases, Bleeding ... PD deficiency, Pulmonary ... emboli • Schistocytes ... , Disseminated intravascular ... #differential #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Paradoxical spontaneous bleeding ... thrombophlebitis, pulmonary ... cryoglobulins • Negative causes ... #rheumatology # ... hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
first trimester pregnancy ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology
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