9 results
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Algorithm Thrombocytopenia ... • Disseminated Intravascular ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... • Mechanical Trauma ... microangiopathy: Thrombotic thrombocytopenic ... lymphoproliferative disorders ... #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
• Rheumatic disorders ... Post-op surgery • Trauma ... following EtOH induced thrombocytopenia ... #Algorithm #Causes ... #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... : - Thrombocytopenia ... Solar purpura - Trauma ... #hematology #rheumatology ... #nonpalpable #dermatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Surgery • Trauma ... Intravenous Drug Use • Pregnancy ... - Disseminated intravascular ... coagulation and other causes ... #hematology #differential
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Disseminated Intravascular ... Recent history of trauma ... protein C and S Pathophysiology ... #Coagulation #diagnosis ... #management #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Liver diseases, Bleeding ... PD deficiency, Pulmonary ... emboli • Schistocytes ... , Disseminated intravascular ... #differential #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Paradoxical spontaneous bleeding ... thrombophlebitis, pulmonary ... cryoglobulins • Negative causes ... #rheumatology # ... hematology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
first trimester pregnancy ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology