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diagnosis hematology management aps algorithm erythematosus eular2019 lupus sle systemic anemia anticoagulation aplastic apml arterial cancer cerebritis cns differential differentiation
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS Venous Thrombosis - Arterial Thrombosis INR Target Duration Recurrence Dr. Laurent ARNAUD
Syndrome) APS ... #Syndrome #APS ... management #EULAR2019 #guidelines ... #rheumatology # ... hematology #treatment
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Syndrome (APS) ... or small-vessel thrombosis ... to be present Treatment ... (EULAR Guidelines ... #Syndrome #APS
2019 EULAR Recommendations - Obstetrics Management in (Antiphospholipid Syndrome) APS Previous Thrombosis? Previous Pregnancy Complications? Dr. Laurent ARNAUD @Lupusreference #obstetrics
Syndrome) APS ... Previous Thrombosis ... #Syndrome #APS ... #rheumatology # ... obgyn #treatment
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperviscosity, TTP, APLS ... • Nephrotic Syndrome ... Malignancy - Antiphospholipid ... antibodies (APLS ... pathophysiology #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... unless severe APLS ... #oncology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid ... Syndrome (APLS) ... Workup Algorithm INDICATIONS ... or small-vessel thrombosis ... #Antiphospholipid
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... vasculopathy, thrombosis ... Puncture, EEG Treatment ... (for secondary APS ... CNS #neurology #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Antiribosomal P, APLA ... disorders • CAD APLA ... activation and/or medications ... Erythematosus #Diagnosis #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... - Antithyroid medications ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment ... Myelodysplastic syndromes ... Network (NCCN) guidelines ... #algorithm #hematology
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