26 results
rheumatology differential symptoms management vasculitis hepatology systemic algorithm autoimmune causes classification clinical dermatology erythematosus hepatopulmonary hypertension inflammatory lupus myopathies myopathy
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
, holster sign, ... anti-synthetase syndrome ... - Classic triad ... at diagnosis). ... #diagnosis #rheumatology
Ramsay Hunt Syndrome - Herpes Zoster Oticus Triad: 1. Ipsilateral facial paralysis 2. Ear pain 3. Vesicles
Ramsay Hunt Syndrome ... Zoster Oticus Triad ... neuropathy • Myelitis ... HerpesZoster #Oticus #Diagnosis ... #Symptoms #Signs
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific ... Anti-Synthetase Syndrome ... MSAs #clinical #diagnosis ... #rheumatology # ... table
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
- Differential Diagnosis ... • Acute stroke syndromes ... Paraneoplastic syndrome ... Lack of UMN/LMN signs ... #Differential #Diagnosis
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... Peptide (CCP) • Myositis ... #diagnosis #associations ... #table
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
heliotrope, shawl sign ... Necrotizing Autoimmune Myositis ... Inclusion Body Myositis ... #comparison #rheumatology ... #table
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... acro-osteolysis, myositis ... overlap • Vascular ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... Glomerulonephritis Myositis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm Pericardial • Effusion • Cardiac Tamponade* • Constriction Myocardial •
- Differential Diagnosis ... Artery Disease • Stable ... Acute Coronary Syndrome ... Arrhythmia • Atrial ... #Differential #Diagnosis
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
• Overlap Myositis ... antisynthetase syndrome ... Inclusion body myositis ... infrequent extra-muscular ... Myopathies #IIMs #diagnosis
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