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management causes algorithm arthritis workup vasculitis anemia dermatology disease hemolytic hepatology joint pain pancytopenia symptoms thrombocytopenia treatment approach classification clinical
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias - Differential ... Diagnosis Algorithm ... Signs of anemia ... Hemolysis: • Autoimmune ... #hematology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... , holster sign, ... anti-synthetase syndrome ... - Classic triad ... #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Diagnosis Algorithm ... methotrexate) • Drugs Autoimmune ... Non-lmmune: • HELLP Syndrome ... #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... Diagnosis Congenital ... Wiskott-Aldrich syndrome ... Inflammatory and Autoimmune ... #Diagnosis #Hematology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Transaminitis - Differential ... Diagnosis • ... Wilson Disease • Vascular ... • Autoimmune ... #hepatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... Kasabach-Merritt syndrome ... #Diagnosis #hematology ... #rheumatology #
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Diagnosis Algorithm ... Autoimmune Mediated ... Autoimmune condition ... HLH syndrome 5. ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... Diagnosis Secondary ... disorders (e.g. autoimmune ... Myelodysplastic syndrome ... #hematology #secondary
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Diagnosis Algorithm ... Autoimmune Mediated ... Autoimmune condition ... HLH syndrome 5 ... #Hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... - Diagnosis and ... thrombocythemia), Autoimmune ... #treatment #hematology ... #differential
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