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diagnosis algorithm bilirubinemia congenital hematology hyperbilirubinemia peds aflp arterial biliary bilirubin cholangitis cirrhosis embolism fatty forms gastroenterology liver management neonatal
Approach to Neonatal Jaundice Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Approach to Neonatal Jaundice ... Causes of pathologic ... Diagnosis #Peds #Pediatrics ... #Algorithm #Differential ... #Workup #bilirubinemia
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Cholangitis #Jaundice ... #Differential # ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Inherited Non-hemolytic ... malaise, are common Crigler-Najjar ... and stress may cause ... Hyperbilirubinemia #Inherited ... Congenital #bilirubin #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... (DIC, ascites, jaundice ... infiltration) Differential ... Liver #Pregnancy #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... hyperpigmentation • Jaundice ... bile ducts Differential ... #hepatology
Inherited forms of Hyperbilirubinemia Major pathways involved in bilirubin production, conjugation, and excretion. Notes: Both the UB
Inherited forms ... Unconjugated Crigler-Najjar ... Hyperbilirubinemia #pathophysiology ... #congenital #hepatology ... #pediatrics #peds
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... thromboembolism • Inherited ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... also JAK2) - Inherited ... you’ll do a good workup ... #Polycythemia #Differential ... Diagnosis #Algorithm #workup
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