11 results
diagnosis algorithm transaminitis hematology injury syndrome ammonia ascites biliary chemistry cholangitis differentiation elevated gap globulin hepatitis hepatorenal hrs hyperammonemia interpretation
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Infiltrative • Cirrhosis ... • Others #LFTs ... #Hepatology #LiverEnzymes ... Diagnosis #Algorithm #Causes
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... CMV), Alcoholic cirrhosis ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Congenital, Others, Cirrhosis ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... /Liver failure ... bile ducts Differential ... diagnosis #workup #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... the study) • Triggers ... ATRA treatment Pathophysiology ... initiation • Differential ... 500 mg QD until normal
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... hepatitis: < 1 • Cirrhosis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
decompensated liver ... myeloma, CML, AML ... Reye syndrome (Peds ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Algorithm Vascular Causes ... function may be abnormal ... hepatitis: < 1 • Cirrhosis ... diagnosis #algorithm #hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Causes of Ascites ... Normal Peritoneum ... - Cirrhosis ... #diagnosis #differential ... #hepatology #SAAG
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
disease: cirrhosis ... • Caused by splanchnic ... Pathophysiology: ... • Normal kidney ... Hepatorenal #Syndrome #Hepatology
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