14 results
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... Smoking, Microbial triggers ... DNA methylation Genetic ... #hepatology
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
the lab values table ... MetabolicEmergency #Genetics ... Diagnosis #Algorithm #Differential ... #Neonatology #Peds ... #Pediatrics #Table
Summary table of comparison of the difference between primary biliary cholangitis (PBC) and primary sclerosing cholangitis
Summary table of ... between primary biliary ... medical diagrams, tables ... #differential #hepatology
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
Metabolism A table ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... #Neonatology #Peds ... #Pediatrics #Table ... #NICU #Genetics
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... on Ultrasound Biliary ... Gallstones • Biliary ... #Jaundice #Differential ... Algorithm #Causes #Hepatology
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Methotrexate Genetic ... congenital - Primary biliary ... #Diagnosis #Differential ... #Hepatology #Cirrhosis
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(GGT) - Liver, biliary ... Conjugated/DBili) - Biliary ... hepatocellular injury, genetic ... conjugation (Gillbert, Crigler-Najjar ... Interpretation #diagnosis #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... No extrahepatic biliary ... bile ducts Differential ... diagnosis #workup #hepatology
Bile Duct Paucity - Differential Diagnosis
 • Genetic: Alagille syndrome, Trisomy 21, Williams syndrome, Peroxisomal disorders
Duct Paucity - Differential ... Diagnosis • Genetic ... duct syndrome, Biliary ... Duct #Paucity #biliary ... #hepatology #Differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... initiation • Differential ... diagnosis #management #hematology