13 results
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Diagnosis and Management ... Perforation) Pathophysiology ... post-ABx, but can ... - produced by all ... #treatment #infectiousdiseases
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
prostaglandin E2 • Triggered ... cause harm as they ... #Hyperthermia #comparison ... #diagnosis #management ... #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
the study) • Triggers ... : ATRA treatment ... Pathophysiology ... Renal Failure Treatment ... APML #diagnosis #management
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
The differential can ... urine osm (in DI ... , Dehydration: neurologic ... also be complex ... #management #nephrology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
ICH Management ... lidocaine, +/- pre-treatment ... reduces ICP (but also ... #neurology #neurosurgery ... #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... complete paralysis of all ... Treatment: • Plasmapheresis ... Syndrome #diagnosis #management ... #treatment #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... nervous system and can ... diagnosis column Treatment ... Lateral #Sclerosis #neurology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... • In all patients ... Pathophysiology ... of NK cells and CD8 ... Treatment Approach
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... HIV and with low CD4 ... Treatment: • HAART ... reversible • HAND is also ... dementia #AIDS #Neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Immune response can ... the underlying pathophysiology ... and cauda equina TREATMENT ... Syndrome #diagnosis #management ... #neurology