11 results
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Perforation) Pathophysiology ... post-ABx, but can ... - produced by all ... ciab549 #CDI #Cdiff ... #infectiousdiseases
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
prostaglandin E2 • Triggered ... production • Treatment ... Cooling blankets can ... cause harm as they ... #Hyperthermia #comparison
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
the study) • Triggers ... : ATRA treatment ... Pathophysiology ... (sepsis), PE, DAH ... Renal Failure Treatment
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... Spontaneous ICH and SAH ... lidocaine, +/- pre-treatment ... reduces ICP (but also ... #neurology #neurosurgery
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... nervous system and can ... proteins like SOD1 can ... diagnosis column Treatment ... Lateral #Sclerosis #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... complete paralysis of all ... Treatment: • Plasmapheresis ... diagnosis #management #treatment ... #neurology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
around day 14 (can ... vary) • Triggered ... See also "Luteal ... #OvarianCycle #pathophysiology ... #comparison #endocrinology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Immune response can ... week • Weakness can ... the underlying pathophysiology ... and cauda equina TREATMENT ... diagnosis #management #neurology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... Treatment: • HAART ... treatment • Cognitive ... reversible • HAND is also ... dementia #AIDS #Neurology
Cryptogenic Organizing Pneumonia - Illness Script

PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... : Unknown trigger ... usually misdiagnosed as ... CAP • Symptoms ... , neoplastic) TREATMENT