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table hematology anticholinergics opioids sympathomimetics syndrome apml cold cop cryptogenic differential differentiation druginduced fungal hemeonc hemophagocytic hlh hyperthermic hypnotics infections
Signs and Symptoms of Toxidromes Sympathomimetic / GABAergic withdrawal Cholinergic Anticholinergic Opioid withdrawal Neuroleptic malignant syndrome Serotonin
Signs and Symptoms ... of Toxidromes ... #Comparison #Table ... Sympathomimetics #Diagnosis ... #Toxicology
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins. There are 5
A toxidrome is a ... syndrome (set of symptoms ... antihistamines #Diagnosis ... #Toxicology #Toxidromes ... #Comparison #Table
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... into serum • Triggers ... Syndrome #TLS #diagnosis ... #management #hematology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
stings Disease trigger ... and duration of symptoms ... angioedema Other symptoms ... #rheumatology # ... comparison #table
Metformin Associated Lactic Acidosis (MALA) Pathophysiology of MALA - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... anaerobic metabolism Diagnosis ... also includes symptoms ... LacticAcidosis #Toxicity #Toxicology ... #Diagnosis #Management
Hyperthermic Toxidromes Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures. • Sympathomimetic -
Five toxidromes ... ryanodine receptor) & triggered ... #comparison #table ... #diagnosis #differential ... #toxicology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... opacities • Diagnosis ... : >3 symptoms, or ... #management #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
blood donor • Pathophysiology ... ARDS to explain symptoms ... transfusion • Pathophysiology ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... constitutional symptoms ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Common Signs and Symptoms ... Pathophysiology ... Approach • Initial management ... #Management #Hematology
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