27 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... : • GH deficiency ... metabolic abn #GrowthHormone ... #FeedbackLoop #endocrinology ... #pathophysiology
Functional Dyspepsia - Pathophysiology, Diagnosis and Management
Risk factors: Non-steroidal anti-inflammatory drugs, Psychological comorbidity, Helicobacter pylori infection,
Functional Dyspepsia ... - Pathophysiology ... Diagnosis and Management ... sex, Smoking Symptoms ... : Bothersome symptoms
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... fraction • HTN #GrowthHormone ... diagnosis #signs #symptoms ... #endocrinology ... #pathophysiology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... : • T4 deficiency ... impairs musde function ... #signs #symptoms ... #endocrinology
Iron Deficiency in Heart Failure - Diagnosis and Treatment Algorithm
Diagnosis: Ferritin <100 ng/mL (absolute ID) OR
Iron Deficiency ... with TSAT <20% (functional ... reasonable to improve functional ... order to alleviate symptoms ... heartfailure #diagnosis #management
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... Heart Failure Pathophysiology ... with TSAT <20% (functional ... improvement in symptoms ... heartfailure #diagnosis #management
Magnesium Deficiency and Alcoholism

Risks associated with Mg deficiency in alcoholism:
 • Affects protein synthesis. energy production,
Magnesium Deficiency ... production, & cell function ... • Depressive symptoms ... • Mg deficiency ... Alcoholism #alcohol #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... Lysis Syndrome: • Pathophysiology ... into serum • Triggers ... TLS #diagnosis #management
Thyroid Function Pathway 

Hypothyroidism is a very common condition! Here's a repost of the pathway that
Thyroid Function ... pathway that is deficient ... Thyroid #Pathway #Pathophysiology ... #Endocrinology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
with vitamin A deficiency ... (shrunken, non-functional ... #Xeropthalmia #pathophysiology ... diagnosis #signs #symptoms