14 results
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
described phases of toxicity ... post-ingestion) - Symptom ... absent in severe toxicity ... #Toxicology #Diagnosis ... #Management #Ferrous
Salicylate Toxicity - Diagnosis and Management

Clinical Findings
Pathophysiology
Workup
Treatment

By Stacy Marshall, MD

#Salicylate #Toxicity #Diagnosis #Management #Toxicology #Aspirin #Treatment
Salicylate Toxicity ... - Diagnosis and ... Findings Pathophysiology ... #Diagnosis #Management ... #Toxicology #Aspirin
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... release Diagnosis ... functional ID) Treatment ... improvement in symptoms ... #management #cardiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... into serum • Triggers ... Syndrome #TLS #diagnosis ... #management #hematology
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... - Diagnosis and ... ingestion/exposure Symptoms ... #Toxicology #diagnosis ... #management #Treatment
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... also includes symptoms ... LacticAcidosis #Toxicity ... #Toxicology #Diagnosis ... #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
the study) • Triggers ... : ATRA treatment ... Pathophysiology ... : >3 symptoms, or ... #management #hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
regarding the diagnosis ... and treatment of ... suspected HH based on symptoms ... hemochromatosis #algorithm #diagnosis ... #management #hepatology
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
starting amiodarone treatment ... gradually with symptoms ... Improvement in symptoms ... macrophages Treatment ... #management #Toxicology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... and Management ... deficiency can lead to iron ... vasculitis Treatment ... #Management