38 results
diagnosis signs hematology management syndrome complications msk disease orthopedics endocrinology leukemia neurology osteoporosis pagetsdisease pediatrics peds psychiatry agammaglobulinemia alkaline alp
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Phosphate Physical Symptoms ... signs, Fragile bones ... easily/weakness, Bone ... pain Psychiatric Symptoms ... Secondary #Tertiary #pathophysiology
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology ... #symptoms #signs
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... #Osteoporosis #pathophysiology ... #signs #symptoms
Osteosarcoma Most common primary malignant bone tumor in children Most Common Sites of Involvement: 1. Distal femur
primary malignant bone ... injury • Systemic symptoms ... Diagnosis #Features #Oncology
Gaucher Disease Pathophsiology • Lysosomal storage disorder • Deficiency of ß-glucocerebrosidase • Accumulation of glucosylceramide in macrophages Diagnosis
Gaucher Disease Pathophsiology ... Osteonecrosis, bone ... Diagnosis #Signs #Symptoms
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... collection with EDTA Pathophysiology ... mineralization Symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Complications #pathophysiology ... #signs #symptoms
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
tear a portion of bone ... lateral hip Signs/Symptoms ... msk #diagnosis #pathophysiology ... #signs #symptoms
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
3: Necrosis of bone ... inner cortical bone ... #Mastoiditis #pathophysiology ... #signs #symptoms ... #diagnosis #otology
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
-> Reduced Bone ... Formation, Increased Bone ... #Osteoporosis #pathophysiology ... #signs #symptoms
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