102 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... mineralization Symptoms ... Difficulty walking Diagnosis ... Hyophosphatasia #hepatology #diagnosis
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
symptoms/signs ... sought to support a diagnosis ... Areas of diagnostic ... mellitus; USS, ultrasound ... #Differential #Diagnosis
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
in macrophages Diagnosis ... in GBA1 gene Clinical ... Osteonecrosis, bone ... Gauchers #Disease #Diagnosis ... #Signs #Symptoms
Rib Fracture on POCUS

There is an interruption in the continuity of this bone (rib), indicated by
continuity of this bone ... Ultrasound is superior ... to X-ray in diagnosing ... Fracture #POCUS #clinical ... #ultrasound #msk
Osteosarcoma 
Most common primary malignant bone tumor in children 
Most Common Sites of Involvement:
1. Distal femur
primary malignant bone ... proximal femur Clinical ... injury • Systemic symptoms ... #Osteosarcoma #Diagnosis
LVOTO due to SAM on POCUS Echocardiogram

Septic patient after IV fluids and initiation of Levophed. Worsening
Diagnosis? ... Robert Jones @RJonesSonoEM ... Echocardiogram #ultrasound ... Cardiology #PLAX #clinical
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Pathogenesis and clinical ... tear a portion of bone ... lateral hip Signs/Symptoms ... Fractures #msk #diagnosis ... pathophysiology #signs #symptoms
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Pathogenesis, clinical ... and underlying bone ... joint capsule or bone ... #Dislocation #Diagnosis ... #signs #symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Tuberculosis - Diagnosis ... extrapulmonary cases Clinical ... Signs/Symptoms: ... back pain - Symptoms ... of bacilli to bone
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Pathogenesis and Clinical ... -> Reduced Bone ... Formation, Increased Bone ... pathophysiology #signs #symptoms ... #diagnosis