26 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
ongoing ↑ LFTs or symptoms ... Idiosyncratic #differential ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... disturbance (obstructed liver ... • Liver (80%) ... Most common symptoms ... symptoms - Pain
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
Hyperbilirubinemia - Differential ... MRCP, ERCP, liver ... direct #bilirubin #Differential ... Diagnosis #Algorithm #gastroenterology ... #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Boxes in yellow ... suspicious clinical symptoms ... Green boxes indicate ... Abnormal #Algorithm #Hepatology ... #Differential #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... : INR/PT, aPTT(liver ... pylori test (GI symptoms ... bypass), LFT (liver ... candidate) - Bone
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Workup • CNS symptoms ... duplex or CTA • Liver ... Liver biopsy • ... values supporting hematologic ... Bone marrow biopsy
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
suspected HH based on symptoms ... , elevated liver ... and hematologic ... diagnosis #management #hepatology ... #gastroenterology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... postpartum): • Initial symptoms ... infiltration) Differential ... #Pregnancy #hepatology
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
• Signs and symptoms ... treatment • Elevated liver ... microscopic colitis Differential ... Diagnosis #Algorithm #gastroenterology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... , bone, placenta ... • softening of bones ... mineralization Symptoms ... Hyophosphatasia #hepatology