24 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... IBD • Chronic liver ... #Osteoporosis #pathophysiology ... #signs #symptoms
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
Subclinical myocardial injury ... : Acute lung injury ... Hepatopulmonary syndrome Bone ... #failure #Signs ... #Symptoms #Diagnosis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Injury (DILI) ... dose dependent injury ... ongoing ↑ LFTs or symptoms ... #differential # ... gastroenterology #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... disturbance (obstructed liver ... • Liver (80%) ... Most common symptoms ... symptoms - Pain
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury ... tear a portion of bone ... onto lateral hip Signs ... msk #diagnosis #pathophysiology ... #signs #symptoms
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... hemolysis) • ALP: Bone ... #differential # ... diagnosis #algorithm #hepatology
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Findings Compression/injury ... MeralgiaParesthetica #MSK #pathophysiology ... #differential # ... diagnosis #signs ... #symptoms
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Boxes in yellow ... suspicious clinical symptoms ... /signs should be ... Abnormal #Algorithm #Hepatology ... #Differential #
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Workup • CNS symptoms ... thin smear • Signs ... Liver biopsy • ... values supporting hematologic ... Bone marrow biopsy