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diagnosis management hematology causes hepatology neurology syndrome clinical msk signs algorithm mri oncology radiology summary workup alkaline classification disease disorders
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... - Highest • Bone ... Most common symptoms ... symptoms - Pain ... #Elevation #Differential
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... collection with EDTA Pathophysiology ... mineralization Symptoms
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... diagnosis #management #pathophysiology
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary Clinical features - Classic triad (flank pain, hematuria,
Symptoms of metastatic ... disease Imaging and Treatment ... Bone scan is indicated ... patients with bone ... , and/or ALP 5.
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Boxes in yellow ... suspicious clinical symptoms ... box indicates all ... ALP, alkaline phosphatase ... Liver #Enzymes #Differential
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... lymphocyte predominant (LP ... pattern of spread, B symptoms ... Responsive to Treatment ... Classification #pathophysiology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Clinical Signs/Symptoms ... back pain - Symptoms ... decreased reflexes Pathophysiology ... of bacilli to bone ... should be done in ALL
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... functional ID) Treatment ... improvement in symptoms ... composite endpoint of all-cause
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... Pathophysiology ... Diagnosis: >3 symptoms ... initiation • Differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... Nucleotidase • ALT ... obstruction • ALP ... bile ducts Differential
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