15 results
diagnosis hematology oncology treatment anemia aplastic hemophagocytic hlh leukemia lymphohistiocytosis myelodysplastic summary activation algorithm cancer carcinoma chronic cll differentiation essential
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... • Bone marrow ... Myelodysplastic #Syndrome ... #MDS #Diagnosis ... #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Diagnosis: >3 symptoms ... Differentiation #Syndrome ... #management #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
(MDS) (normal or ... Hypocellular/Hypoplastic MDS ... • Improve the symptoms ... Anemia #oncology #hematology ... #diagnosis #management
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Diagnosis and Management ... Hypercellular bone ... transformation into AML ... or MDS ... PV #Diagnosis #Management
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Script Signs and symptoms ... with hypocellular bone ... Can progress to MDS ... Anemia #diagnosis #management ... #treatment #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
hemophagocytosis in the bone ... CD163 staining of bone ... is found in the bone ... #Diagnosis #Management ... #Hematology #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(MDS) What? ... age 70 years Symptoms ... platelets) • MDS ... progression to AML ... #diagnosis #hematology
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary Clinical features - Classic triad (flank pain, hematuria,
Diagnosis and Management ... Budd Chiari syndrome ... Symptoms of metastatic ... Bone scan is indicated ... patients with bone
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Warm AIHA • Bone ... • Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia • Sezary syndrome
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