19 results
Atrioventricular Septal Defect
aka AV canal defect aka endocardial cushion defect
 • Epidemiology and Associations
 • Embryology
Defect aka AV canal ... Physical Exam • Pathophysiology ... Post-Operative ICU ... Outcomes by Cara
Midcarpal Instability (MCI) of the Wrist

Intrinsic Midcarpal Instability
Usually affects young, hypermobile patients.
It is due to progressive
The proximal carpal ... wrist extensors (ECU ... ECRB) The distal carpal ... clinical #video #physicalexam
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Hypothyroidism – symptoms ... Symptoms: Tiredness ... peripheries, Carpal ... Features #Signs #Symptoms ... #Diagnosis #PhysicalExam
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... overgrowth: • Carpal ... diagnosis #signs #symptoms ... endocrinology #pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... expansion (e.g. carpal ... endocrinology #pathophysiology
Classic Findings During Hallpike Test in Posterior Canal Benign Paroxysmal Positional Vertigo (BPPV)
 • Latency (delay
Test in Posterior Canal ... Reproduction of vertigo symptoms ... #dixhallpike #physicalexam
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
in the Spinal canal ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
boggy" joints, esp carpal ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Scoliosis: Pathogenesis and clinical findings (Cobb Angle > 10 Degrees)

 • Incr Axial rotation of thoracic
intervertebral canal ... #Scoliosis #pathophysiology ... diagnosis #signs #symptoms
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... organ dysfuxtion, ICU