11 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... , holster sign, ... anti-synthetase syndrome ... , and arthritis ... Can also see mechanics
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
of hip (rare), Arthritis ... Demyelinating syndromes ... Glomerulonephritis Myositis ... erythematosus #signs ... #symptoms #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
matter, spinal cord ... Behcet disease) Differential ... Oral aphthae : SLE ... : SLE, Reactive ... diagnosis #management #signs
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential ... and signs below ... - Transverse myelitis ... Behcet disease - SLE ... MCTD, Sjogren syndrome
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Manifestations: - Arthritis ... anemia 4% - Myositis ... autoantibodies #signs ... #symptoms #mimickers ... #differential #
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... and/or symptoms ... Evaluate for NMO, SLE ... Disorders: - SLE ... management #neurology #differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... ), Sjogren's Syndrome ... , Sjögren Syndrome ... , Myositis, Mixed ... rheumatology #diagnosis #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, inflammatory arthritis ... permanent alopecia Differential ... Arthritis: • ... • Transverse Myelitis ... Induced Lupus: • Symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... Conjunctivitis, mucositis ... Presentation - Systemic Symptoms ... purpura: strong sign ... vasculitis, and SLE
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms