16 results
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Rheumatoid arthritis ... , esp carpal, MCP ... fingers, radial wrist ... Extra-articular signs ... #symptoms #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
of hip (rare), Arthritis ... Demyelinating syndromes ... Glomerulonephritis Myositis ... erythematosus #signs ... #symptoms #diagnosis
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... - (Reiter’s syndrome ... Erythematosus (SLE ... should have other symptoms ... #Diagnosis #Algorithm
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... , holster sign, ... anti-synthetase syndrome ... , and arthritis ... Can also see mechanics
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Diagnosis Framework ... • Sciatica • Tarsal ... • Myositis/pyomyositis ... #diagnosis #lower
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Manifestations: - Arthritis ... anemia 4% - Myositis ... autoantibodies #signs ... #symptoms #mimickers ... #differential #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... Joint #pain #Differential ... #Diagnosis #MSK
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... Behcet disease) Differential ... Oral aphthae : SLE ... : SLE, Reactive ... #signs #symptoms
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... , Sjögren Syndrome ... , Myositis, Mixed ... #rheumatology #diagnosis ... #differential
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
inflammation of the joints ... Episcleritis Signs ... and Symptoms: ... and pain of the joints ... #diagnosis #dermatology