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diagnosis differential hematology algorithm management workup classification hemolysis oncology atlas clinical macrocytic macrocytosis mcv blood dermatology elevatedmcv extravascular folate folicacid
Anemia - Workup and Differential Diagnosis - History, Physical Exam, Labs - Microcytic - Normocytic -
Anemia - Workup ... Exam, Labs - Microcytic ... - Hemolytic # ... Anemia #Workup # ... Differential #Diagnosis #causes
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Reticulocytes • Abnormal ... Anemias (AIHAs) ... Anemias (AHAs) ... Diagnosis #Algorithm #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Anemia 1) DIAGNOSE ... AIHA • Anemia ... : macrocytic > normocytic ... 2) LOOK FOR a cause ... management #treatment #rheumatology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Framework by MCV Microcytic ... -100): • Non-hemolytic ... , CKD • Hemolytic ... Infections Macrocytic ... Differential #Diagnosis #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... - Abnormal RBCs ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... → Sickle Cell anemia ... Hypochromic & microcytic ... anemia (TTP, HUS ... Diagnosis #Algorithm #causes
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Hemolytic #Anemia ... #Differential #Causes ... #Workup #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Morphology Atlas • Microcytic ... Lead poisoning • Macrocytic ... spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... #differential #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Normal range 11.5% ... acute blood loss, hemolysis ... for degree of anemia ... Diagnosis #Workup #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... antibiotics are the most frequently ... Extravascular #Causes ... #anemia
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