26 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Generally affects long bones ... • XR, MRI to ... BrighamChiefs #Bone
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
fragmentation and mild bone ... possible secondary ossification ... • MRI is more sensitive ... tibial tuberosity Differential ... marrow edema and bony
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... • Bone and joint ... Rule out other causes ... - MRI: inflammation ... osteoarticular and skin disease
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
g/dl LLN B - Bony ... more: • Clonal bone ... focal lesions on MRI ... Causes of false- ... plasmacytoma, POEMs syndrome
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... due to increased bone ... failure, Addison's disease ... calcium)-alkali syndrome ... #differential #
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
D) Increased bone ... of bone Malignancy ... Multiple myeloma (bone ... • Milk-alkali syndrome ... endocrinology #diagnosis #differential
Primary and Secondary Causes of Osteoporosis

Primary osteoporosis 
 - idiopathic juvenile osteoporosis 
 -  postmenopausal
and Secondary Causes ... Cushing syndrome ... intolerance Bone ... plasmacytoma) - diffuse bone ... #Differential #
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... Postparathyroidectomy (hungry bone ... metastasis (hungry bone ... Tubulointerstitial renal disease ... #diagnosis #differential
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Peripheral Vascular Disease ... fractured long bone ... Marfan's Syndrome ... • Dislocated Bone ... #Orthopedics #Causes
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Short Stature - Differential ... • Cushing's Disease ... Chemotherapy • Bone ... Transplant Chronic Disease ... endocrinology #causes