36 results
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... storage disorder • Deficiency ... #Gauchers #Disease ... Diagnosis #Signs #Symptoms
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
PIP Involvement, Spares ... Scleritis, Heart Disease ... Nodules, Pulmonary Disease ... RA #diagnosis #rheumatology ... #signs #symptoms
Magnesium Deficiency and Alcoholism

Risks associated with Mg deficiency in alcoholism:
 • Affects protein synthesis. energy production,
Magnesium Deficiency ... atherosclerotic CVS disease ... • Depressive symptoms ... • Mg deficiency ... Alcoholism #alcohol #pathophysiology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... anti-coagulation • Hematologic ... -> Cherry-red spot ... Occlusion #CRAO #pathophysiology ... diagnosis #signs #symptoms
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Signs of Copper Deficiency ... Inflammatory bowel disease ... Chronic diarrhoea, Short ... drkeithsiau #Copper #Deficiency ... #riskfactors #symptoms
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... : • GH deficiency ... : - Short ... endocrinology #pathophysiology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
with vitamin A deficiency ... conjunctiva) • Bitot's spots ... #Xeropthalmia #pathophysiology ... diagnosis #signs #symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... Clinical Signs/Symptoms ... decreased reflexes Pathophysiology ... Residency @CMC_IM #Potts ... #Disease #Tuberculosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Protein S deficiency ... - Protein C deficiency ... Myeloproliferative disease ... Venous #Arterial #pathophysiology ... #hematology #differential
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
stages of this disease ... The signs and symptoms ... late stages of disease ... reddish brown spots ... Clinical #Photo #Dermatology