58 results
Rheumatoid arthritis (RA): X-ray features
 • Soft tissue swelling (best seen by comparing left & right
Narrowing • Bony ... the articular bone ... #RA #HandXray #Diagnosis ... #Radiology #Clinical ... #Pathophysiology
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
Osteoarthritis (OA): Clinical ... in subchondral bone ... contact between bony ... Osteoarthritis #OA #pathophysiology ... #diagnosis #signs
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Syndrome #PUBS #pathophysiology ... #clinical #photo ... #differential #diagnosis
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
Pathogenesis and Clinical ... tenderness • Positive one-legged ... vertebrae • CT - collar ... Spondylolisthesis #MSK #diagnosis ... #pathophysiology
Diagnosing Brucellosis
Epidemiological Exposures
- Endemic Regions
- Clinical Micro Lab Technicians
- Animal/Vaccine Exposure: Vets, Slaughterhouse workers, hunters
- Unpasteurized
Diagnosing Brucellosis ... Endemic Regions - Clinical ... cheese, ice cream) Clinical ... Neurological, Ocular ... Culture (blood, bone
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
Pathogenesis and clinical ... 3: Necrosis of bone ... destroying thin bony ... #Mastoiditis #pathophysiology ... signs #symptoms #diagnosis
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... collection with EDTA Pathophysiology ... Difficulty walking Diagnosis ... Hyophosphatasia #hepatology #diagnosis
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... in macrophages Diagnosis ... in GBA1 gene Clinical ... Osteonecrosis, bone ... Gauchers #Disease #Diagnosis
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Pathogenesis, clinical ... and underlying bone ... joint capsule or bone ... #Dislocation #Diagnosis ... #orthopedics #pathophysiology
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Pathogenesis and Clinical ... -> Reduced Bone ... Formation, Increased Bone ... #Osteoporosis #pathophysiology ... signs #symptoms #diagnosis