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diagnosis signs management behavioraldisorder bulimianervosa hematology msk ophthalmology anorexianervosa ascorbicacid conversion criteria differential disorders endocrinology erythematosus essential et femoralhead fractures
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
signs, Fragile bones ... easily/weakness, Bone ... /joint pain Psychiatric ... Symptoms: Disorientation ... Secondary #Tertiary #pathophysiology
Osteoarthritis (OA): Clinical findings • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
in subchondral bone ... contact between bony ... Osteoarthritis #OA #pathophysiology ... diagnosis #signs #symptoms ... #complications
Somatoform Disorders - Differential Diagnosis Algorithm - Patient presents with complex medical problem or symptoms that
Differential Diagnosis Algorithm ... Somatoform Disorder - One ... or more symptoms ... Differential #Diagnosis #Algorithm ... #Psychiatry
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in one ... Retinoblastoma Signs / Symptoms ... / Complications ... Retinoblastoma #pathophysiology ... diagnosis #signs #symptoms
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
tear a portion of bone ... lateral hip Signs/Symptoms ... /Complications: ... msk #diagnosis #pathophysiology ... #signs #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... /Complications: ... Infertility • Decr Bone ... Syndrome #genetics #pathophysiology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Hypercellular bone ... When present, symptoms ... , signs, and complications ... • "Vasomotor" symptoms ... • Treatment algorithms
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Mucous membranes • Bone ... • Persons with psychiatric ... musculoskeletal symptoms ... Psychiatric symptoms ... #AscorbicAcid #Pathophysiology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... cause excessive bone ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms ... #complications
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