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diagnosis msk complications peds disease endocrinology management orthopedics psychiatry syndrome wrist behavioraldisorder bones causes genetics geriatrics gh growthhormone ophthalmology ossification
Triquetral Fracture The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
commonly fractured carpal ... bone. ... "pooping duck sign ... bone fracture ... "pooping duck sign
Ossification of Carpal Bones It’s always tricky to remember the age of ossification of the carpal bones
Ossification of Carpal ... ossification of the carpal ... interpreting a Pediatric ... -6-7 years for Triquetral ... Diagnosis #Peds #Pediatrics
Age of Ossification of Carpal Bones Capitate - 1 Month Hamate - 2 Months Triquetral - 3 Years Lunate -
Ossification of Carpal ... Bones Capitate ... Hamate - 2 Months Triquetral ... bones! ... diagnosis #msk #pediatrics
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology ... #symptoms #signs
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... activates lipolysis Signs ... /Symptoms: • GH ... expansion (e.g. carpal ... endocrinology #pathophysiology
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
: Commonly no signs ... , Fragile bones/ ... easily/weakness, Bone ... pain Psychiatric Symptoms ... Secondary #Tertiary #pathophysiology
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... #Osteoporosis #pathophysiology ... #signs #symptoms
Osteoarthritis (OA): Clinical findings • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
in subchondral bone ... contact between bony ... Osteoarthritis #OA #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... Infertility • Decr Bone ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings Pars interarticularis stress fracture (spondylolysis) - most frequently in the
tenderness • Positive one-legged ... XR — scotty dog sign ... MSK #diagnosis #pathophysiology ... #signs #symptoms
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