28 results
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Flow cytometry, Bone ... and Screen for HLH ... HLH syndrome 5. ... Alcoholism Bone ... Diagnosis #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Flow cytometry, Bone ... and Screen for HLH ... HLH syndrome 5 ... Alcoholism Bone ... Diagnosis #Algorithm #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Lymphohistiocytosis (HLH ... ) Clinical Features ... lab findings in HLH ... consistent with HLH ... Lymphohistiocytosis #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... accumulation of clinical ... , Biological + Bone ... /ml, ↑ LDH • Bone ... treatment #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... : Overwhelming clinical ... / Diagnosis: HLH ... Hemophagocytosis in bone ... management #treatment #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... fever syndromes Clinical ... Fever is the main clinical ... Diagnosis #Management #Hematology ... #Rheumatology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
algorithm for bone ... significance (MGUS) A bone ... whom there are no clinical ... diagnosis #management #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • softening of bones ... Neuropathy ALP is critical ... collection with EDTA Pathophysiology ... Hyophosphatasia #hepatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... subtypes: - Nodular ... (LDHL) - Nodular ... anymore • Routine bone ... classification #hematology
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Pathogenesis and Clinical ... Sex Hormones (LH ... -> Reduced Bone ... Formation, Increased Bone ... #Osteoporosis #pathophysiology