30 results
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
algorithm for bone ... ) A bone marrow ... , low-risk MGUS ... whom there are no clinical ... diagnosis #management #hematology
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
significance (MGUS ... ) Mayo Clinic Risk ... monoclonal #gammopathy #MGUS ... diagnosis #management #hematology
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
IgM #gammopathy #MGUS ... #Clinical #Pathology ... #Hematology #Smear
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS ... Monoclonal #Gammopathy #Clinical ... #Significance #MGUS ... Differential #Diagnosis #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
level <3 g/dL • Bone ... g/dL • Clonal bone ... insufficiency, Anemia, and Bone ... disorder • Clonal bone ... #Significance #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• MM • WM • MGUS ... • MGCSMGRS ... Dermato-neuro syndrome) MGRS ... Hypergammaglobulinemic macular ... Paraproteinemias #Hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
more: • Clonal bone ... #Gammopathies #MGUS ... #diagnosis #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • softening of bones ... Neuropathy ALP is critical ... collection with EDTA Pathophysiology ... Hyophosphatasia #hepatology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Significance (MGUS ... osteoclast activity and bone ... resorption - Bone ... rituximab (in clinical ... Complications #diagnosis #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
prognosis • Nodular ... • Classic - Nodular ... Classification #pathophysiology ... #Hematology #Diagnosis