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diagnosis signs hematology causes management msk oncology joint pain ra rheumatology syndrome anemia aortitis approach arteritis biliary bone cardiology checklist
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
in Sickle Cell Disease ... other orthopedic complications ... Osteomyelitis / Septic Arthritis ... • Differentiate ... #differential #
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
- Arthralgia, Arthritis ... Weakness, Incr CK • Bone ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
• Ligament • Bone ... or nerve root Symptoms ... the subchondral bone ... rheumatology #approach #workup ... #differential #
Aortitis - Diagnosis and Workup Clinical History: - Fever, weight loss, deterioration of general health - Aortic
Diagnosis and Workup ... hypertension) - Symptoms ... Inflammatory diseases ... , Takayasu arteritis ... #Differential #
Highlighted Conditions With Arteritis or Periarteritis of the Coronaries Takayasu's arteritis: - Onset < 40 yrs -
yrs - Cranial symptoms ... IgG4-related disease ... Erdheim-Chester disease ... : - Bone pain ... #Differential #
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
tear a portion of bone ... /Complications: ... weight-bear • Arthritic ... msk #diagnosis #pathophysiology ... #signs #symptoms
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... PT, aPTT(liver disease ... pylori test (GI symptoms ... candidate) - Bone
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: ... Complications ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms ... #complications
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis ... - Signs and Symptoms ... , Complications ... Bursa, Muscle, Bone ... #RA #Signs #Symptoms
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... but elevated as disease ... bile ducts Differential ... cholangitis #diagnosis #workup
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