83 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Algorithm ALP ... stimulation (placenta/Bone ... - Highest • Bone ... Intestine - Other causes ... - Bone symptoms
Paget's Disease of Bone

 • Characterized by an ↑ rate of bone turnover with both excessive
by an ↑ rate of bone ... and formation of bone ... • Caused by ( ... #Bone #diagnosis ... #management #treatment
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver, bone ... Most cases diagnosed ... • softening of bones ... of feet, thigh bones ... : Inhibitor of bone
Bone Lesion on X-Ray - Differential Diagnosis Algorithm 
Exostotic
 • Osteochondroma
Asymptomatic &/or Non-Active Bone Scam
 •
Bone Lesion on X-Ray ... /or Non-Active Bone ... • Unicameral Bone ... Constitutional Symptoms ... #Causes
Amyloidosis - Workup and Diagnostic Algorithm
 • Serum Immunofixation and Serum Free Light Chains
 • Biopsy
Algorithm • Serum ... skin, fat pad, bone ... tests after AL ... chain ratio • Bone ... marrow biopsy • Echocardiogram
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm
True Vertigo - Illusion of Rotary Movement
Peripheral Vestibular
Causes of Dizziness ... Algorithm True ... • Meniere's Disease ... Media • Temporal Bone ... #Algorithm #Causes
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
- Differential Diagnosis ... Algorithm Elevated ... Granulomatous Disease ... Miscellaneous - Bone ... #Algorithm #causes
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
- Differential Diagnosis ... Algorithm Tumours ... - See Bone Lesions ... • Bone Marrow ... #Causes
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: ... excessive bone ... turnover -> Incr bone ... pathophysiology #diagnosis ... #signs #symptoms
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Carcinoma (RCC) - Diagnosis ... Symptoms of metastatic ... and Treatment - ... Bone scan is indicated ... patients with bone