22 results
diagnosis oncology anemia differential algorithm management monoclonal blood causes gammopathy mds myelodysplastic pancytopenia product reactions significance treatment agglutinin calculation chronic
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Increased red cell ... hyperplasia of bone ... Increased red cell ... Differential #Causes #Workup ... #Hematology #Diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
• Marrow Aplasia ... Bleed • Hemolysis ... RBCs - Sickle Cells ... , Target Cells ... Algorithm #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
marrow failure: Aplastic ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... defects (e.g. sickle cell ... Production #Index #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle cells ... Consider sickle cell ... Diagnosis #Algorithm #workup ... #hematology #testing
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Alcoholism Bone ... FISH • Acquired Aplastic ... #Pancytopenia #Workup ... Diagnosis #Algorithm #Hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... with hypocellular bone ... Consider stem cell ... Medicine @SCVMCMed #Aplastic ... management #treatment #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... marrow plasma cells ... to the plasma cell ... marrow plasma cells ... #Significance #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Alcoholism Bone ... FISH • Acquired Aplastic ... #Pancytopenia #Workup ... Diagnosis #Algorithm #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... aplasia • ITP ... Warm AIHA • Bone ... Leukemia #diagnosis #workup ... #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
= Hypocellular bone ... Hypoplastic MDS: • ↓ bone ... • Suggested by bone ... hypoplasia/fatty bone ... Anemia #oncology #hematology
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