20 results
diagnosis oncology management anemia differential algorithm causes pancytopenia treatment blood monoclonal myelodysplastic product reactions atopic atopy calculation chronic classification cll
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... FISH • Acquired Aplastic ... • Hypoplastic MDS ... #Pancytopenia #Workup ... Diagnosis #Algorithm #Hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... with hypocellular bone ... Consider stem cell ... Can progress to MDS ... management #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... = funny-shaped cells ... • Bone marrow ... Myelodysplastic #Syndrome #MDS ... Management #treatment #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... FISH • Acquired Aplastic ... • Hypoplastic MDS ... #Pancytopenia #Workup ... Diagnosis #Algorithm #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
= Hypocellular bone ... myelodysplastic syndrome (MDS ... Hypocellular/Hypoplastic MDS ... abnormalities typical for MDS ... Anemia #oncology #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... marrow plasma cells ... to the plasma cell ... marrow plasma cells ... #Significance #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
or basket cells ... aplasia • ITP ... Warm AIHA • Bone ... Leukemia #diagnosis #workup ... #oncology #hematology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Increased red cell ... hyperplasia of bone ... Increased red cell ... Differential #Causes #Workup ... #Hematology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes (MDS ... formed or don’t work ... Causes • Anemia • Aplastic ... Workup: • Complete ... Syndromes #diagnosis #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
Hypoproliferative (i.e. bone ... Hypogonadism • Bone ... marrow failure: Aplastic ... defects (e.g. sickle cell ... Production #Index #hematology
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