18 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... of thrombocytopenia ... TTP/HUS indicates ... purpura/hemolytic ... , Hematology 2012
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
HUGE treatment ... and first-line treatment ... #purpura #TTP # ... #thrombocytopenia ... Diagnosis #Table #Hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Thrombocytopenic ... HUS) Treatment ... #Purpura #management ... #treatment #rheumatology ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Drug induced - Bone ... disease - DIC/TTP/HUS ... : • DIC, TTP/HUS ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Petechiae • Purpura ... DDX: • TMA’s (HUS ... - MAHA: TTP/HUS ... + Bleeding Treatment ... #management #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... diagnosed annually in US ... • Bone marrow ... only curative treatment ... #treatment #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
(Petechial or purpuric ... leukopenia, anemia, and thrombocytopenia ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
= Hypocellular bone ... infections/fevers • Thrombocytopenia ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Atopic Dermatitis - Topical Treatment Options 
First Line: Topical Corticosteroids 
  - High Potency: Betamethasone
Dermatitis - Topical Treatment ... products do not work ... and patient has ... #Pharmacology #Dermatology ... #Management