20 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... - TTP VS HUS ... #thrombocytopenic ... #purpura #TTP # ... Diagnosis #Table #Hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... of thrombocytopenia ... TTP/HUS indicates ... purpura/hemolytic ... , Hematology 2012
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Primary Thrombotic Microangiopathy ... • Thrombotic Thrombocytopenic ... Purpura (TTP) ... Primary #Thrombotic #Microangiopathy ... #TMA #hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
of Thrombotic Thrombocytopenic ... Purpura (TTP) ... TMA: Thrombotic microangiopathy ... HUS) Treatment ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Drug induced - Bone ... disease - DIC/TTP/HUS ... : • DIC, TTP/HUS ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... folate def - Bone ... Consumption: - Microangiopathy ... : DIC, TTP, HUS ... Diagnosis #Framework #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Mechanical Trauma (Microangiopathic ... : Thrombotic thrombocytopenic ... purpura (TTP), ... uremic syndrome (HUS ... differential #diagnosis #hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Thrombotic Microangiopathy ... triad of MAHA + thrombocytopenia ... TTP (atypical HUS ... #Thrombotic #Microangiopathy ... #TMAs #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... candidate) - Bone ... or if a primary hematologic ... Diagnosis #Causes #Workup ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Petechiae • Purpura ... Hemorrhagic bullae • Purpura ... DDX: • TMA’s (HUS ... - MAHA: TTP/HUS ... treatment #management #hematology