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diagnosis management algorithm anemia differential workup cll pancytopenia chronic classification disorders lymphocytic myelodysplastic product reactions treatment acute aml apl apml
Map of proliferative blood disorders. By Ariella Coler-Reilly @ariellastudies #Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
proliferative blood ... proliferative #blood ... #disorders #leukemia ... #hematology #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
• Bone marrow ... transformation to acute leukemia ... Myelodysplastic #Syndrome #MDS ... Management #treatment #hematology ... #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... with hypocellular bone ... Can progress to MDS ... or acute leukemia ... management #treatment #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... virus (EBV) • Leukemia ... result from low blood ... #Anemia #oncology ... #hematology #diagnosis
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... (blood). ... Kyle Bradley, MD ... promyelocytic #leukemia ... APML #Pathology #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... blast cells - Blood ... CLL -> Invade Skin ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... Lymphocytosis: Absolute blood ... Pure red cell aplasia ... Warm AIHA • Bone ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Flow cytometry, Bone ... Alcoholism Bone ... FISH • Acquired Aplastic ... • Hypoplastic MDS ... Diagnosis #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Flow cytometry, Bone ... Alcoholism Bone ... FISH • Acquired Aplastic ... • Hypoplastic MDS ... Diagnosis #Algorithm #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
the peripheral blood ... Hypogonadism • Bone ... marrow failure: Aplastic ... > 3: • Acute blood ... Production #Index #hematology
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