8 results
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
algorithm for bone ... patients with monoclonal ... significance (MGUS) A bone ... #monoclonal #gammopathy ... diagnosis #management #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... sub-types based on the hematologic ... level <3 g/dL • Bone ... g/dL • Clonal bone ... #Significance #hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma and Monoclonal ... more: • Clonal bone ... if this is is monoclonal ... Other causes of a monoclonal ... MGUS #diagnosis #hematology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
AlkP) - Liver, bone ... brain, NOT in bone ... pancreas, NOT in bone ... #Tests #LFTs #Laboratory ... Interpretation #diagnosis #hepatology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... deficiency - Anemia - Bone ... LiverFailure #Hepatic #Hepatology ... #Laboratory #Diagnosis
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Other locations: bone ... Chemistry #Tests #Laboratory ... AlkPhos #Bilirubin #Hepatology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Complications of Monoclonal ... osteoclast activity and bone ... resorption - Bone ... Renal disease - Monoclonal ... Complications #diagnosis #hematology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
plasmacytoma of bone ... • Occur in bone ... ) or outside bone ... tissue composed of monoclonal ... Diagnosis #Workup #Hematology