79 results
Hashitoxicosis

‘Leakage’ symptoms of active Hashimoto’s disease

- Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
Hashitoxicosis ‘Leakage’ symptoms ... thyroiditis that causes ... - In the early stages ... ‘Leakage’ symptoms ... Endocrinology #Diagnosis #Pathophysiology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
mechanical loading => Bone ... strain => Bone ... StressFractures #msk ... #orthopedics #pathophysiology ... #symptoms #signs
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
signs, Fragile bones ... osteoporosis, Kidney stones ... easily/weakness, Bone ... pain Psychiatric Symptoms ... Secondary #Tertiary #pathophysiology
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
with possible symptoms ... patellofemoral joint with MRI ... Patellofemoral #Syndrome #pathophysiology ... diagnosis #signs #symptoms ... #msk
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long bones ... • XR, MRI to ... dx and stage ... differential #diagnosis #causes
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... spine Signs / Symptoms ... suspected, immediate MRI ... CaudaEquina #Syndrome #MSK ... #pathophysiology
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
Osgood-Schlatter Disease - MSK ... fragmentation and mild bone ... • MRI is more sensitive ... tear (similar symptoms ... patella #clinical #mri
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Abnormal Osteoclasts cause ... formation MSK ... Nephrolithiasis (Kidney Stones ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
Otitis Media -> Stage ... are connected) Stage ... hearing loss, nausea ... #Mastoiditis #pathophysiology ... #signs #symptoms