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diagnosis differential management signs symptoms rheumatology causes msk hematology neurology treatment algorithm radiology endocrinology pocus ophthalmology physicalexam hepatology oncology orthopedics
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... Leukemia) • GI diseases ... liver or kidney disease ... #Osteoporosis #pathophysiology
Vertebral Body Abnormalities A sheet of common (and uncommon) vertebral body findings, because a completely “normal” spine
Vertebra Hurler Syndrome ... Morquio Syndrome ... Hemivertebra Scheuermann Disease ... Sclerotic Mets Bone ... Diagnosis #Vertebrae #diseases
Rheumatoid arthritis (RA): X-ray features • Soft tissue swelling (best seen by comparing left & right
the articular bone ... Peri-articular osteopenia (bones ... Diagnosis #Radiology #Clinical ... #Pathophysiology
Hypocalcemia - Diagnosis and Management PTH Independent (↑ PTH) • LOW VIT D -
Activation: Liver disease ... , Kidney Disease ... - Accelerated Bone ... Formation: Hungy Bone ... Syndrome -
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Pathogenesis and clinical ... =>Prader-Willi Syndrome ... Infertility • Decr Bone ... #genetics #pathophysiology
Gaucher Disease Pathophsiology • Lysosomal storage disorder • Deficiency of ß-glucocerebrosidase • Accumulation of glucosylceramide in macrophages Diagnosis
Gaucher Disease ... Pathophsiology ... in GBA1 gene Clinical ... Osteonecrosis, bone ... #Gauchers #Disease
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
treatment of renal bone ... disease and cinacalcet ... which reduces bone ... #Pharmacology #Pathophysiology
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 SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... SAPHO syndrome is ... Rheumatic pain Clinical ... Diagnosis: • A clinical ... osteoarticular and skin disease
Patterns of Diseases on MRI FLAIR - Differential Diagnosis ADEM, Adreno-leukodystrophy, CADASIL, CNS, Lymphoma, High-Grade Glioma, HIV
Patterns of Diseases ... Vessel Ischemic Disease ... , Susac Syndrome ... FLAIR #Patterns #Diseases ... neuroradiology #clinical
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Flow cytometry, Bone ... HLH syndrome 5. ... Alcoholism Bone ... marrow failure syndrome ... Metastatic Disease
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