19 results
Triquetral Fracture
The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
fractured carpal bone ... "pooping duck sign ... " on lateral x-ray ... common carpal bone ... " on lateral x-ray
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
Osteoporosis: Pathogenesis ... 30 (post-peak bone ... Decr estrogen • Bone ... #pathophysiology ... #signs #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
clinical findings • Maternal ... Prader-Willi Syndrome Signs ... Infertility • Decr Bone ... mineral density and osteoporosis ... Syndrome #genetics #pathophysiology
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Symptoms: Commonly no signs ... , Fragile bones/ ... osteoporosis, Kidney ... easily/weakness, Bone ... Secondary #Tertiary #pathophysiology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Amyotrophic Lateral ... examination finding of amyotrophy ... sclerosis Pathophysiology ... Edaravone #ALS #Amyotrophic ... #neurology #diagnosis
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Glucocorticoid-Induced Osteoporosis ... -> Reduced Bone ... Formation, Increased Bone ... #pathophysiology ... #signs #symptoms
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... Osteonecrosis, bone ... infarcts, osteoporosis ... Disease #Diagnosis #Signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Normal CK • Osteoporosis ... Complications #pathophysiology ... #signs #symptoms
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
young people) • Osteoporosis ... exerted onto the lateral ... Bisphosphonate suppresses bone ... damage weakens the bone ... differential #causes #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
tear a portion of bone ... from impact onto lateral ... hip Signs/Symptoms ... msk #diagnosis #pathophysiology ... #signs #symptoms