82 results
Triquetral Fracture
The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
The triquetrum ... fractured carpal bone ... "pooping duck sign ... common carpal bone ... "pooping duck sign
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Symptoms: Commonly no signs ... , Fragile bones/ ... easily/weakness, Bone ... Secondary #Tertiary #pathophysiology
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
of Malignancy - Pathophysiology ... D - Increased renal ... resorption in the bone ... resorption in the bone ... Cell of lung, Renal
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology ... #symptoms #signs
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... #Osteoporosis #pathophysiology ... #signs #symptoms
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment of renal ... bone disease and ... which reduces bone ... #Pharmacology #Pathophysiology
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Summary Clinical Signs ... hyperCalcemia 28% (bone ... demineralization) • Renal ... • Anemia 78% (bone ... macrocytic • Bone
Lung POCUS: Shred sign in patient with non-translobar consolidation. Phased array probe used.

Dr. Robert Jones @RJonesSonoEM

#ShredSign
Lung POCUS: Shred sign ... Robert Jones @RJonesSonoEM ... POCUS #Pulmonary #Ultrasound
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• softening of bones ... of feet, thigh bones ... collection with EDTA Pathophysiology ... neuropathy • Renal ... : - Renal failure
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... Osteonecrosis, bone ... Disease #Diagnosis #Signs