55 results
diagnosis signs syndrome complications management msk disease orthopedics differential pth calcium cushings deficiency diabetes fractures genetics gh growthhormone hematology neurology
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
signs, Fragile bones ... /osteoporosis, Kidney ... easily/weakness, Bone ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
Osteoporosis: Pathogenesis ... 30 (post-peak bone ... Decr estrogen • Bone ... #pathophysiology ... #signs #symptoms
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Glucocorticoid-Induced Osteoporosis ... -> Reduced Bone ... Formation, Increased Bone ... #pathophysiology ... #signs #symptoms
Gaucher Disease Pathophsiology • Lysosomal storage disorder • Deficiency of ß-glucocerebrosidase • Accumulation of glucosylceramide in macrophages Diagnosis
Gaucher Disease Pathophsiology ... Osteonecrosis, bone ... infarcts, osteoporosis ... Diagnosis #Signs #Symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Normal CK • Osteoporosis ... Complications #pathophysiology ... #signs #symptoms
Bisphosphonates for Osteoporosis Treatment or Prevention Bisphosphonates are common medications used in the treatment and prevention
Bisphosphonates for Osteoporosis ... prevention of osteoporosis ... turn increase bone ... #Pharmacology #Endocrinology ... #Osteoporosis #
Diabetes Insipidus vs Syndrome of Inappropriate ADH (SIADH) - Comparison Table Diabetes Insipidus - Inadequate ADH SIADH -
Comparison #Table #Pathophysiology ... #Signs #Symptoms ... #Diagnosis #Endocrinology
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus Calcium - Net Effect Hypercalcemia: ↑ intestinal
absorption ↑ bone ... Hypophosphatemia: ↑ bone ... Calcium #Phosphorus #pathophysiology ... #endocrinology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... Infertility • Decr Bone ... mineral density and osteoporosis ... Syndrome #genetics #pathophysiology
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology ... #symptoms #signs
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