14 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... decr activity, nutrition ... #Osteoporosis #pathophysiology ... #signs #symptoms
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
dental fixatives, Treatment ... /jejunal nutrition ... Musculoskeletal: Low bone ... #riskfactors #symptoms ... #nutrition
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
initiation of nutrition ... overload) Other Symptoms ... hyperparathyroidism Treatment ... #Differential # ... Diagnosis #Pathophysiology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Mucous membranes • Bone ... musculoskeletal symptoms ... Psychiatric symptoms ... vasculitis Treatment ... #Nutrition #Diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... pattern of spread, B symptoms ... Responsive to Treatment ... growth, response to treatment ... Classification #pathophysiology
Tongue Pathology 

Geographic tongue, fissured tongue, and hairy tongue are the most common tongue problems and
do not require treatment ... an underlying nutritional ... require biopsy to differentiate ... has responded to treatment ... duration, antecedent symptoms
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Diagnosis: >3 symptoms ... initiation • Differential ... Renal Failure Treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Transplantation including bone ... Etiology: • Pathophysiology ... Neurological symptoms ... Reversible course Differential ... epilepticus Treatment
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Platelet Disorders • Nutritional ... factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
surgery, trauma, and bone-marrow ... than one after symptom ... the underlying pathophysiology ... and cauda equina TREATMENT