36 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• softening of bones ... of feet, thigh bones ... mineralization Symptoms ... neuropathy • Renal ... : - Renal failure
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Highest • Bone ... Most common symptoms ... Pregnancy - Renal ... disease - Bone ... symptoms - Pain
Colchicine Toxicity 
Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly]
2-24 hrs 
 • Severe GI distress
2-7 days • Bone ... Rhabdomyolysis • Renal ... Toxicity #Toxicology #Symptoms
Horseshoe Kidney on Transverse Abdominal POCUS

Dr. Robert Jones @RJonesSonoEM

#Horseshoe #Kidney #Transverse #Abdominal #POCUS #Renal #Ultrasound #Clinical
Robert Jones @RJonesSonoEM ... Abdominal #POCUS #Renal ... #Ultrasound #Clinical
Malignant Bone Tumors: Pathogenesis of X-ray appearance

 • Metastatic bone tumors (aka. cancerous cells from systemic
Malignant Bone Tumors ... • Metastatic bone ... • Metastatic bone ... . thvroid. and renal ... Signs/Symptoms:
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Renal Cell Carcinoma ... palpable abdominal renal ... Symptoms of metastatic ... Bone scan is indicated ... patients with bone
Normal prominent medullary pyramids on renal POCUS
No hydronephrosis. Has prominent medullary pyramids. They can appear markedly
medullary pyramids on renal ... they taper toward renal ... Robert Jones @RJonesSonoEM ... medullary #pyramids #renal ... POCUS #clinical #ultrasound
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Boxes in yellow ... suspicious clinical symptoms ... shown in the grey boxes ... Green boxes indicate ... mellitus; USS, ultrasound
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
cause excessive bone ... turnover -> Incr bone ... Pathologic fractures Renal ... , Incr renal [Ca2 ... diagnosis #signs #symptoms
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
phosphorous in bones ... high-resolution ultrasound ... Disease #Signs #Symptoms