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diagnosis hematology wrist management msk oncology pathophysiology pediatrics radiology age anemia aplastic chronic cll endocrinology feedbackloop fracture gh growthhormone lymphocytic
Age of Ossification of Carpal Bones Capitate - 1 Month Hamate - 2 Months Triquetral - 3 Years Lunate -
Age of Ossification ... of Carpal Bones ... Hamate - 2 Months Triquetral ... of the carpal bones ... #Age #Carpal #Bones
Ossification of Carpal Bones It’s always tricky to remember the age of ossification of the carpal bones
Ossification of ... Carpal Bones ... of the carpal bones ... -6-7 years for Triquetral ... #Carpal #Bones
Triquetral Fracture The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
commonly fractured carpal ... bone. ... bone fracture ... • Complications ... #Wrist #Carpal
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... rapid onset of symptoms ... chronic onset of symptoms ... B-cell lineage ALL Symptoms ... Transformation: • Complication
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... chondrocytes -> Incr ossification ... lipolysis Signs/Symptoms ... expansion (e.g. carpal
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... with no early symptoms ... kinase (BTK) Complications ... Warm AIHA • Bone ... • GI complications
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Script Signs and symptoms ... with hypocellular bone ... neutropenic fever) Complications ... to MDS or acute leukemia
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... cause excessive bone ... the vertebral canal ... diagnosis #signs #symptoms ... #complications
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